DRC member Eric Taylor leads a study that suggests new metabolic target for liver cancer

Director of the FOEDRC Metabolomics Core Facility, Eric Taylor, PhD is the lead investigator in a new study that finds that disrupting a metabolic pathway in the liver in a way that creates a more “cancer-like” metabolism actually reduces tumor formation in a mouse model of liver cancer.

Because liver cancer is the fifth most common cancer worldwide and continues to rise, factors that cause it, such as obesity and diabetes are becoming more common. The results were surprising because disrupting the mitochondrial pyruvate carrier (MPC) promotes a more cancer-like metabolism, with cells increasing their use of glucose and an amino acid called glutamine to produce energy.

Click here to read the whole article. 

 

 

Leave a Reply

Fill in your details below or click an icon to log in:

WordPress.com Logo

You are commenting using your WordPress.com account. Log Out /  Change )

Google photo

You are commenting using your Google account. Log Out /  Change )

Twitter picture

You are commenting using your Twitter account. Log Out /  Change )

Facebook photo

You are commenting using your Facebook account. Log Out /  Change )

Connecting to %s

%d bloggers like this:
search previous next tag category expand menu location phone mail time cart zoom edit close