In a recent study in JCI Insight conducted by Dr. E. Dale Abel and other members of the Abel Laboratory have identified an important link between insulin resistance and diabetic heart failure.
Previously, the Abel Laboratory has revealed that exposure of the heart to higher levels of insulin may expedite heart failure when heart damage occurs. In the most recent study Insulin receptor substrates differentially exacerbate insulin-mediated left ventricular remodeling explains what signals within the cell trigger this event.
