On Sunday, March 24, 2019 Abel Laboratory member, Jesse Cochran presented at the Endocrine Society’s annual meeting in New Orleans. Under the mentorship of E. Dale Abel, Cochran studied both male and female mice. He fed them either a ketogenic diet or a regular diet as a control for 15 weeks.
The control diet consisted of 7 percent fat, 47 percent carbohydrates and 19 percent protein by mass, whereas the ketogenic diet was 75 percent fat, 3 percent carbohydrates and 8 percent protein by mass.
The female mice on the ketogenic diet displayed no changes in weight and had impaired blood sugar control compared with females on the control diet. The male mice, however, displayed a decrease of body weight when on the ketogenic diet while blood sugar control was maintained. Those male mice on the ketogenic diet did display signs of worsened non-alcoholic fatty liver disease.
After removing the ovaries in some female mice and retesting both diets Cochran concluded that, “this finding suggests that postmenopausal women could potentially experience better weight loss outcomes with the ketogenic diet compared to younger women.”
Updated: April 2, 2019.
Since Cochran’s study has been published, it has continued to gain more news coverage. Here are some links to other articles.